Antivirulence Genes: Insights into Pathogen Evolution through Gene Loss
نویسندگان
چکیده
منابع مشابه
Black holes, antivirulence genes, and gene inactivation in the evolution of bacterial pathogens.
The evolution of bacterial pathogens from nonpathogenic ancestors is marked principally by the acquisition of virulence gene clusters on plasmids and pathogenicity islands via horizontal gene transfer. The flip side of this evolutionary force is the equally important adaptation of the newly minted pathogen to its new host niche. Pathoadaptive mutations take the form of modification of gene expr...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2012
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00740-12